A consistency-based consensus algorithm for de novo and reference-guided sequence assembly of short reads

Tobias Rausch, Sergey Koren, Gennady Denisov, David Weese, Anne-Katrin Emde, Andreas Döring, and Knut Reinert

About

Sequence consensus "./seqcons" is an open source consensus computation program for Linux and Windows. The algorithm can be used for de novo and reference-guided sequence assembly.

Binaries and source code for ./seqcons

You can find executables of our implementation in the download section. The source code can be accessed via the SeqAn SVN.

Usage

./seqcons -r <Multi-Fasta File> [Options]
./seqcons --help
 

References

Rausch, T., Koren, S., Gennady, D., Weese, D., Emde, A.-K., Döring, A., Reinert, K. (2009). A consistency-based consensus algorithm for de novo and reference-guided sequence assembly of short reads. Bioinformatics.

Rausch, T., Emde, A.-K., Reinert, K. (2008). Robust consensus computation. BMC Bioinformatics.

 

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