Segment-based multiple sequence alignment

Tobias Rausch, Anne-Katrin Emde, David Weese, Andreas Döring, Cedric Notredame, Knut Reinert

About

SeqAn::T-Coffee is an open source multiple sequence alignment program. SeqAn::T-Coffee aligns amino acid, DNA and RNA sequences using a consistency-based progressive alignment algorithm on a graph of sequence segments.

Binaries and source Code for SeqAn::T-Coffee

You can find executables of our implementation in the download section. The source code can be accessed via the SeqAn SVN.

Usage

./seqan_tcoffee -s <Fasta Sequence File> [Options]
./seqan_tcoffee --help

References

Rausch, T., Emde, A.-K., Weese, D., Doring, A., Notredame, C., and Reinert, K. (2008). Segment-based multiple sequence alignment. Bioinformatics, 24(16), i187–192.

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